Posts Tagged ‘Cancer’

Many postmenopausal women are looking for alternatives to hormone therapy, especially in light of the recent Women’s Health Initiative research findings concerning the risks of combined estrogen and progestin therapy. Of particular interest are phytoestrogens, which have been gaining popularity due to their “natural” status, alleged health claims, and availability in a wide range of foods and supplements.

What are Phytoestrogens?

Phytoestrogens are naturally occurring plant compounds that have some similarities to estradiol, the most potent naturally occurring estrogen. However, phytoestrogens tend to have weaker effects than most estrogens, are not stored in the body, and can be easily broken down and eliminated.

Observational studies have found a lower prevalence of breast cancer, heart disease and hip fracture rates among people living in places like Southeast Asia, where diets are typically high in phytoestrogens. In North America, knowledge of these reported health effects has stimulated great interest in the health benefits of phytoestrogens. According to the Food and Drug Administration, the sale of soy foods, a major source of phytoestrogens, has increased dramatically in the past decade.

Dietary Sources of Phytoestrogens

Phytoestrogens consist of more than 20 compounds and can be found in more than 300 plants, such as herbs, grains and fruits. The three main classes of dietary phytoestrogens are isoflavones, lignans and coumestans:

1. Isoflavones (genistein, daidzein, glycitein and equol) are primarily found in soy beans and soy products, chickpeas and other legumes.

2. Lignans (enterolactone and enterodiol) are found in seeds (primarily flaxseed), cereal bran, legumes, and alcohol (beer and bourbon).

3. Coumestans (coumestrol) can be found in alfalfa and clover. Most food sources containing these compounds typically include more than one class of phytoestrogens.

The Skeletal Effects of Phytoestrogens

Much of the evidence concerning the potential role of phytoestrogens in bone health is based on animal studies. In fact, soybean protein, soy isoflavones, genistein, daidzein and coumestrol have all been shown to have a protective effect on bone in animals who had their ovaries surgically removed.

In humans, however, the evidence is conflicting. Compared to Caucasian populations, documented hip fracture rates are lower in countries such as Hong Kong, China and Japan where dietary phytoestrogen intakes are high. Yet reports suggest that Japanese women have a greater risk of sustaining a vertebral fracture than Caucasian women.

Several studies have explored the effects of soy isoflavones on bone health, but results have been mixed, ranging from a modest impact to no effect. Most of these studies have serious limitations, including their short duration and small sample size, making it difficult to fully evaluate the impact of these compounds on bone health.
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We hear it all the time…lose weight for your health. Few people however, realize the extent to which this is critical to their physical well-being and ultimately their life expectancy.

In January 2003, the Journal of the American Medical Association featured a study finding that obesity appears to lessen life expectancy, especially among young adults. The researchers compared Body-Mass Index (BMI) to longevity and found a correlation between premature death and higher BMIs. For example, a 20-year-old white male, 5’10” weighing 288 pounds with a BMI of greater than 40 was estimated to lose 13 years of his life as a result of obesity.Jamie McManus, M.D., F.A.A.F.P. and author of “Your Personal Guide to Wellness” notes that while this study referenced extreme levels of obesity, there are still millions of overweight people in developed countries with a life expectancy rate that is three to five years less than their healthy-weight counterparts. She also estimates that there are 600,000 obesity related deaths each year in America.

Just how does obesity shorten our lifespan? The answer to this question is complex, yet there is a clear link between obesity and the development of cancer. An extensive study conducted by the American Cancer Institute involving 750,000 people showed that obesity significantly increased the risk of cancer developing in the following organs: breast, colon, ovaries, uterus, pancreas, kidneys and gallbladder.

Michael Thun, MD, vice-president of epidemiology and surveillance research for the American Cancer Society (ACS) says one reason obesity may raise cancer risk is because fat cells produce a form of estrogen called estradiol that promotes rapid division of cells, increasing chances of a random genetic error while cells are replicating, which can lead to cancer. In addition, fat centered around the abdomen may increase insulin and insulin-like growth factors in the blood, which may increase cancer risk.

“Women who are obese after menopause have a 50% higher relative risk of breast cancer,” notes Thun, “and obese men have a 40% higher relative risk of colon cancer…. Gallbladder and endometrial cancer risks are five times higher for obese individuals”.There is evidence that cancer rates in developed countries are increasing at 5 to 15 times faster than developing countries. A major contributor to this alarming reality has proven to be diet. In populations where the diet consists mostly of fresh fruit and vegetables and whole grains – in contrast to the typical Western diet of fatty meats, refined flours, oils and sugars – the risk of cancer is much lower.
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Our hormone health effects our bodies in many ways but one specific way is an increase in weight. Hormonally challenged women gain weight around their middle between the armpits and the top of the thighs. Often their arms are normal, their legs are normal and from the neck up they look great! Hormonally challenged men gain weight around their waists and often are on their way to developing breasts!

Estrogen is produced in our fat cells. Estrogen increases fat cells. As a result more estrogen is produced and so on and so on.

Breaking the Estrogen cycle and then going on an excellent weight management program is exactly what needs to take place.

Step One Evaluate your hormones. Find out the ratio of estrogen to progesterone presently in your body. If out of balance, we call that estrogen dominance, then you will likely have or currently be gaining weight around your middle.

Step Two Begin an estrogen-lowering program. That will include of course increasing your progesterone levels with a bio-identical progesterone cream. But hormone balancing was never all about progesterone. Modulating and balancing estrogens if found to be out of balance to progesterone is equally important to your weight loss program.
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A heart attack is known as a myocardial infarction. This occurs when the heart muscle is damaged or does not receive enough oxygen. Many cardiac related problems occur due to blockages in arteries that carry purified blood away from the heart to different parts of the body. Another cause is the formation of blood clots.

Very often, it is quite difficult to differentiate between a heart attack and heartburn. The common signs of a heart attack are a tightness, pain, or discomfort in the chest. Sweating, nausea, and vomiting that are accompanied by intense pressure in the chest. A radiating and intense pain in the chest that extends from the chest to the left arm. A shortness of breath for more than a few minutes. If you have any of the above you must consult the doctor or go to the emergency rooms.

If you even think you are having a heart attack you must call for a cardiac care ambulance, and put under your tongue a sorbitrate or chew an aspirin. If you are allergic to aspirin don’t take one. At the hospital care will include rapid thrombolysis, cardiac catheterization, and angioplasty. They will also administer intravenously clot busting medications.

The risk factors for a heart attack include: smoking, diabetes, high levels of cholesterol, hypertension, family history of heart diseases, atherosclerosis, lack of exercise, obesity, and fast foods.
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